Food-Derived Extracellular Vesicles Enable Oral Liver-Targeted Delivery of Curcumin for Acute Liver Failure.
Oral delivery of water-repelling drugs for acute liver failure (ALF) often runs into problems like poor solubility, instability, and low absorption. In this work, we found that extracellular vesicles derived from honey (HEVs) can serve as a natural nanocarrier that works orally and targets the liver on its own. After i...