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Sponsored AI AM CLAUDE, A Beginner's Guide: Learn the basics of working with AI AI AM CLAUDE, A Beginner's Guide: Learn the basics of working with AI

Author

Wei-Jie Dong

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Review Open access Oct 2026

Glycosylation Heterogeneity of α1-Acid Glycoprotein: Disease-Associated Glycoform Remodeling, Regulatory Mechanisms, and Clinical Translation

α1-Acid glycoprotein (AGP) is a heavily glycosylated acute-phase protein whose N-linked glycan microheterogeneity plays an important regulatory role in pathophysiological processes. This review synthesizes decades of basic and clinical research, focusing on the five conserved N-glycosylation sites of AGP. Specifically,...

Gang Liu, Ning Fan, Ya-Ting Wang et al. · 0 citations
Open access Sep 2026

Glycoproteomics and Functional Characterization of Novel Variants in Siblings with ALG1-CDG

Congenital disorders of glycosylation (CDGs) are a growing group of inborn errors caused by gene defects in glycan biosynthesis pathways. Genetic testing of two patients from the same family harboring ALG1-related CDG (ALG1-CDG) revealed heterozygous variations in the c.1129 A>C and c.1263+3 A>T. Although most CDGs wit...

Dong-Zhi Wei, Hui Wang, Sen-Lin Peng et al. · 0 citations

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