PHD1/IKKβ/NF-κB signaling pathway regulates macrophage polarization and is involved in hypoxia-tolerant large yellow croaker (Larimichthys crocea) against Aeromonas hydrophila infection.
The hypoxia-tolerant group (T group) large yellow croaker (Larimichthys crocea) exhibits high survival rates when infected with Aeromonas hydrophila. To elucidate the underlying mechanism, this study explored the potential new role of proline hydroxylase domain-containing protein 1 (PHD1) in immunity, and examined the...