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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

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Wei Liu

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Open access Sep 2026

Molecular Grammar of Intrinsically Disordered Regions: How Sequence and Context Shape Biomolecular Condensation and Disease

Intrinsically disordered regions (IDRs) are central components of many biomolecular condensates, where their sequence features help shape the weak and multivalent interactions underlying assembly and regulation. Aromatic and charged residues, sequence patterning, repeat motifs, and spacer properties can influence inter...

Wei Liu, Sulin Lou · 0 citations

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