Cuproptosis is a form of programmed cell death reported in 2022, characterized by copper ions directly binding to mitochondrial lipoylated proteins, inducing aberrant protein aggregation and destabilizing iron-sulfur cluster proteins, ultimately leading to cell death. Distinct from apoptosis, ferroptosis, and other kno...
Peng-Peng Li, Yang-Yang Gao, Wei Liu· Frontiers in Cell and Develo...· 0 citations
A testable precision medicine paradigm integrating multimodal biomarkers to identify high risk individuals and guide targeted interventions is proposed to improve long term outcomes in this vulnerable population of stroke patients.