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Review Open access Sep 2026

Roles of cuproptosis in central nervous system tumors: from molecular mechanisms to therapeutic prospects

Cuproptosis is a form of programmed cell death reported in 2022, characterized by copper ions directly binding to mitochondrial lipoylated proteins, inducing aberrant protein aggregation and destabilizing iron-sulfur cluster proteins, ultimately leading to cell death. Distinct from apoptosis, ferroptosis, and other kno...

Peng-Peng Li, Yang-Yang Gao, Wei Liu · 0 citations
Review Open access Jul 2026

Brain heart crosstalk after ischemic stroke toward a unified framework for pathophysiology and precision medicine

A testable precision medicine paradigm integrating multimodal biomarkers to identify high risk individuals and guide targeted interventions is proposed to improve long term outcomes in this vulnerable population of stroke patients.

Peng-Peng Li, Yang-Yang Gao, Wei Liu · 0 citations

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