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Review Oct 2026

RNA-Dependent RNA Polymerase (RdRp): Structure, Function, and Antiviral Targeting in RNA Viruses.

RNA-dependent RNA polymerase (RdRp) is the core catalytic enzyme that mediates RNA viral replication and transcription. The polymerase facilitates template and substrate channel assembly, nucleotide selectivity, and phosphodiester bond formation, making it an essential component of the viral life cycle. RdRps differ gr...

Wei Liu, Yi-Yi Feng, Fan-Xin Liu et al. · 0 citations

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