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Review Oct 2026

The ACOD1-itaconate axis in anti-neuroinflammation and protection against neurodegenerative diseases.

Chronic neuroinflammation mediated by activated microglia constitutes a central pathogenic mechanism underlying neurodegenerative diseases, including Alzheimer's disease (AD), Parkinson's disease (PD), and multiple sclerosis (MS). Despite substantial progress in elucidating disease mechanisms, effective disease-modifyi...

Da-Hui Wang, Jensen G. Weedor, Natasha M. Weah et al. · 0 citations

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