Open access
Sep 2026
Versatile Microgel Platform for Intervertebral Disc Degeneration Therapy: Targeting Pericyte‐Mediated Fibrosis and Protecting Nucleus Pulposus Cells
This study identified pericytes as novel fibrotic effector cells in IVDD, contributing to fibrosis through activation of the TGF‐β signaling pathway, and developed a microgel platform designed to specifically inhibit pericyte activation and pro‐fibrotic transition.
Fei Ma, Zhen Zhao, Chuan Guo et al.
· Advancement of science · 0 citations