Wei-Qiang Zhang

Radical–carbanion relay enabled by earth-abundant titanium: carboxylation of 1°, 2°, and 3° benzyl chlorides with CO2

The catalytic conversion of CO2 into arylacetic acids is of significant interest owing to the prevalence of these scaffolds in nonsteroidal anti-inflammatory drugs (NSAIDs) and fine chemicals. However, existing methods remain constrained by limited substrate scope, reliance on precious metals, or the need for stoichiom...