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Wei-Qin Lu

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Sep 2026

A novel mTORC1-NPC2 axis suppresses lipophagy and drives atherosclerotic plaque progression.

Hypercholesterolemia disrupts endothelial lipophagy through the mTORC1-NPC2 signaling axis, promoting lipid accumulation and accelerating atherosclerosis, and targeting this pathway may offer a novel therapeutic strategy for AS.

Le-Gao Chen, Wei-Qin Lu, Long Piao et al. · 0 citations

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