Open access
Sep 2026
Sex-specific physical activity thresholds influencing muscle function in older adults with XX genotype of ACTN3 R577X
Physical activity is widely recommended to maintain muscle health in older adults, yet its effects may vary depending on genetic background. The ACTN3 R577X polymorphism leads to α-actinin-3 deficiency in XX homozygotes and may influence skeletal muscle performance. We examined the association between physical activity...
Hsiu-Ching Hsu, Wen-Hui Fang, Meng-Chang Lee et al.
· Scientific Reports · 0 citations