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Sponsored AI AM CLAUDE, A Beginner's Guide: Learn the basics of working with AI AI AM CLAUDE, A Beginner's Guide: Learn the basics of working with AI

Author

Wei Wang

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Open access Sep 2026

Loss of ADAMTS9 disrupts ciliogenesis and collagen homeostasis resulting in Nephronophthisis-like polycystic kidneys.

ADAMTS9 mutations cause the ciliopathies nephronophthisis and Joubert syndrome. Here we demonstrated that deletion of ADAMTS9 in the proximal nephron led to polycystic kidney development in mice. In males, Adamts9 deletion caused kidneys to become highly cystic while remaining small without undergoing enlargement. In c...

Sydney Fischer, Karyn L. Robert, Manu Ahmed et al. · 0 citations
Open access Aug 2026

Dysregulated Ferritin and Iron Homeostasis in Autosomal Dominant Polycystic Kidney Disease.

Ferritin dysregulation is implicated in numerous pathological conditions, however, its role in autosomal dominant polycystic kidney disease (PKD) remains poorly understood. Ferritin expression is increased in cyst-lining epithelial cells and macrophages in both PKD mouse and human kidneys. To investigate the functional...

Nicole Sommer, Sagine Placide, Elizabeth Weatherly et al. · 0 citations

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