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Open access Aug 2026

Learning Enzyme Optimal pH Ranges from Multimodal Molecular Representations.

DeepPH is a structure-aware framework that models enzyme optimal pH as an interval regression problem to capture inherent uncertainty and outperforms existing methods under both standard and interval-aware evaluations and generalizes well to extreme-length sequences.

Wei Wang, Po-Yu Liang, Jun Bai · 0 citations

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