Open access
Aug 2026
POSTN⁺ CAF–SPP1⁺ macrophage crosstalk is associated with immune exclusion and poor prognosis in lung adenocarcinoma
A spatially organized POSTN⁺ CAF–SPP1⁺ macrophage niche that may contribute to stromal remodeling, CD8⁺ T-cell exclusion, and potentially reduced immunotherapy benefit in LUAD is defined.
Ankang Zhu, Jian-Yuan Huang, Juan Zhang et al.
· Journal of Translational Med... · 0 citations