MTR4 deficiency attenuates abdominal aortic aneurysm progression through suppressing VSMC senescence via the MTR4-RAP1a axis
Summary Abdominal aortic aneurysm (AAA) is a life-threatening vascular disease characterized by progressive aortic dilation, with insidious onset but high mortality after rupture and limited treatment options. Vascular smooth muscle cell (VSMC) senescence is a key driver of AAA progression. RNA helicase MTR4 has been r...