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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

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Wei-Wei Jiang

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Review Open access Aug 2026

URMylation Signaling Pathway in Cancer: Molecular Mechanisms and Therapeutic Opportunities

Ubiquitin-related modifier 1 (URM1) defines a distinctive ubiquitin-like system in which URM1 functions both as a covalent protein modifier and a sulfur carrier required for wobble uridine (U34) thiolation of cytosolic tRNAs. This dual role places URM1 signaling at the intersection of protein post-translational modific...

Jing-Chao Wang, Pei-Qiang Yan, Wei-Wei Jiang et al. · 0 citations

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