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Open access Sep 2026

FANCD2 knockdown suppresses malignant phenotypes and is associated with caspase/PARP-mediated apoptosis in NCI-H2052 pleural mesothelioma cells.

Background Malignant pleural mesothelioma (PM) is a highly aggressive thoracic malignancy with an extremely poor prognosis and limited effective therapeutic strategies, representing a critical unmet clinical need. Fanconi anemia complementation group D2 (FANCD2) is a critical effector of the cellular DNA damage respons...

Ying-Fang Xiang, Pu Su, Rui-Ying Zhang et al. · 0 citations
Review Oct 2026

Emerging roles of long non-coding RNA CASC2 in tumor chemoresistance - a review.

Malignant tumors remain a leading cause of global mortality, and the development of chemoresistance represents a major obstacle to effective cancer treatment. Long non-coding RNAs (lncRNAs) are important regulators of tumor progression and therapeutic response. Cancer susceptibility candidate 2 (CASC2) is an lncRNA tha...

Ling-Yun Zhou, Jin-Tao He, Wen-Bing Huang et al. · 0 citations
Review Open access Sep 2026

Long non-coding RNA GAS6-AS1 and its molecular mechanisms in human cancer (Review)

GAS6-AS1 represents a promising molecule for understanding cancer pathogenesis and developing novel strategies for precision cancer diagnosis and treatment, although further clinical validation and mechanistic studies are still required.

Zhi-Ling Lu, Wen-Bing Huang, Jin-Tao He et al. · 0 citations

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