Open access
Oct 2026
Astragaloside IV attenuates ferroptosis-related testicular injury in rats with experimental varicocele
Varicocele is an important correctable cause of male infertility. Oxidative stress and lipid peroxidation contribute to the associated testicular injury, but the role of ferroptosis remains controversial. Astragaloside IV (AS-IV), a quality-control metabolite of Astragali radix, has antioxidant activity and can modul...
Bo Gao, Sheng-Jing Liu, Meng Sun et al.
· Frontiers in Pharmacology · 0 citations