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Open access Sep 2026

Gut microbiota dysbiosis is associated with the synaptic deficits and cognitive impairment induced by LCM mixtures within a proposed mechanistic framework consistent with the AOP concept.

Liquid crystal monomers (LCMs), as emerging environmental contaminants, have poorly understood cognitive effects under realistic mixture exposure scenarios. This study integrated ecological and human exposure data to characterize LCM mixtures and assessed their neurotoxicity using in vitro and in vivo models. We found...

Lian-Rui Duan, Jia-Yi Liang, Wei Zhang et al. · 0 citations
Aug 2026

YTHDF3-Dependent m6A Modification of cGAS Drives Nanoparticle-Induced Senescence in Spermatocytes.

BACKGROUND Nanoplastics (NPs), owing to their small size and ability to cross the blood-testis barrier, pose a potential risk to the male reproductive system. However, the molecular mechanisms underlying NP-induced reproductive toxicity, particularly cell senescence, remain poorly understood. OBJECTIVES This study ai...

Jia-Yi Liang, Wei Zhang, Hui Kang et al. · 0 citations

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