Electroacupuncture Alleviates Functional Constipation by Activating HSF1-Dependent Mitochondrial Unfolded Protein Response in Colonic Smooth Muscle Cells.
BACKGROUND & AIMS Functional constipation (FC) is closely associated with impaired gastrointestinal motility and mitochondrial dysfunction. Electroacupuncture (EA) has shown therapeutic potential in FC; however, the underlying cellular and molecular mechanisms remain incompletely understood. We investigated whether EA...