A KRAS-ERK-associated model for molecular stratification and prognosis prediction: Highlighting the tumorigenic role of ARNTL2 in KRAS-mutant pancreatic cancer.
Pancreatic ductal adenocarcinoma (PDAC) remains one of the most lethal malignancies, characterized by poor survival rates and limited therapeutic options. Oncogenic KRAS mutations are frequent in pancreatic cancer patients and are key drivers of tumorigenesis. Recent studies have underscored the essential role of extra...