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Author

Weisong Mo

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Aug 2026

CTSB promotes ferroptosis in macrophage-derived foam cells and aggravates plaque instability via the NRF2/HMOX1 axis.

A CTSB/NRF2/HMOX1 signaling cascade that drives ferroptosis in macrophage-derived foam cells and promotes plaque instability is uncovered, positioning CTSB as a promising therapeutic target for stabilizing high-risk atherosclerotic plaques.

Fan Gong, Xiaobin Wang, Weisong Mo et al. · 0 citations

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