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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

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Weiyan Xu

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Open access Aug 2026

CRISPR/Cas9-Mediated PD-1 Engineered T Cells: New Strategy to Block Tumor Immune Escape

At present, overexpression of immune-related genes is one of the key mechanisms of tumor immune evasion. As a tumor cell-mediated immune escape core checkpoint molecule, the PD-L1 (programmed death ligand 1) will recruit SHP-1/SHP-2 (Src homology phosphotyrosyl phosphatase 1/ Src homology phosphotyrosyl phosphatase 2)...

Weiyan Xu · 0 citations

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