Open access
Aug 2026
De Novo Molecular Design and Bioactivity Prediction of Novel Hexahydroquinolines as Plasmodium falciparum Calcium-Dependent Protein Kinase 4 (CDPK4) Inhibitors
This study aimed to design novel HHQs as potential PfCDPK4 inhibitors with good binding affinity, favourable pharmacokinetics, and structural stability, and provided biologically meaningful computational evidence supporting HHQ scaffolds as potential PfCDPK4 inhibitors.
G. Oduselu, D. Bodun, O. Ajani et al.
· Bioinformatics and Biology I... · 0 citations