Open access
Sep 2026
The dual role of recombinant IL-33 in acute liver failure: hepatoprotection versus lethal systemic inflammation.
BACKGROUND AND AIMS Interleukin-33 (IL-33), a member of the IL-1 family, participates in immune regulation and tissue repair, but its role in acute liver failure (ALF) remains unclear. This study investigated the effects and mechanisms of recombinant IL-33 in a concanavalin A (Con A)-induced murine ALF model. METHODS...
Mei-Xin Gao, Meng-Qi Li, He-Rui Wei et al.
· European Journal of Pharmaco... · 0 citations