Open access
Sep 2026
SIRPγ promotes CD8⁺ T cell exhaustion via metabolic-epigenetic reprogramming in tuberculous pleural effusion
Previous studies have shown that signal regulatory protein γ (SIRPγ) is an important regulatory factor for T cell function. However, its expression and biological role in tuberculous pleural effusion (TPE) remain unknown. In this study, we find that the level of SIRPγ is significantly upregulated in TPE compared to n...
Yue-Ning Yang, Qian-Qian Xue, Si-Dao Wang et al.
· Nature Communications · 0 citations