Treatment-resistant depression (TRD) is characterized by persistent symptoms and poor response to conventional therapies, yet its dynamic neural mechanisms and treatment-related changes remain incompletely understood. This study applied a hidden Markov model (HMM) combined with neurotransmitter atlas mapping to investi...
Tan Li, Le-Yi Zhang, Yi-Ding Han et al.· Neurotherapeutics· 0 citations
Neuroimaging studies in obsessive-compulsive disorder (OCD) have yielded heterogeneous findings, limiting efforts to localize OCD to specific brain regions or networks. This study applied coordinate network mapping (CNM) to test whether these distributed abnormalities converge onto a common brain network and to explore...
These findings identify distinct cortical morphometric organization in BDD and MDD, and these differences are linked to transcriptomic, cellular, and neurotransmitter-related annotations, providing multiscale insights into the neurobiological divergence between the two disorders.
Guang-Wei Sun, Tai-Peng Sun, Yu-Cheng Yuan et al.· Psychiatry and Clinical Neur...· 0 citations
This study further elucidated the neuroimaging changes underlying across-diagnostic dissociation and provided new insights for identifying network intervention targets to improve dissociative symptoms.
Xu-Han Cui, Le-Yi Zhang, Y. Ou et al.· Psychiatry and Clinical Neur...· 0 citations
BACKGROUND
Although structural and functional alterations in borderline personality disorder (BPD) have been widely reported in neuroimaging studies, the findings remain heterogeneous. Emerging consensus suggests that these distributed alterations may converge on a common pathological network associated with BPD, provi...
Le-Yi Zhang, Yi-Ding Han, Y. Ou et al.· Journal of Affective Disorde...· 0 citations
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