Author

Wen-Bo Zhang

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Open access Sep 2026

Treatment modalities and survival outcomes among elderly patients with stage IV small-cell lung cancer and synchronous brain metastases: A retrospective seer-based cohort study.

OBJECTIVE Chemotherapy improves survival in patients with lung cancer. However, the prognostic associations linked to chemotherapy remain unclear in elderly patients with stage IV small-cell lung cancer (SCLC) and brain metastases. This retrospective study was performed to explore the prognostic associations of differe...

Wen-Bo Zhang, Jian-Wei Gu, Xiao-Jun Xiang et al. · Cancer Treatment and Researc... · 0 citations

Sep 2026

Targeting PPP1R14B overcomes immunotherapy resistance in prostate cancer by restoring CD8+ T-cell infiltration via the Nrf2/CX3CL1 axis.

Prostate cancer (PCa) is typically immunologically 'cold', which limits the effectiveness of immunotherapy, and this study sought to identify key genes driving this immunosuppressive phenotype and assess their therapeutic potential. We analyzed transcriptomic data from 487 TCGA-PRAD patients and three Gene Expression O...

Jie Yang, Chuan Zhou, Wen-Bo Zhang et al. · Journal of Pathology · 0 citations

Review Open access Aug 2026

The predictive value of abnormal uteroplacental and fetal Doppler indices for adverse perinatal outcomes in hypertensive disorders of pregnancy: a systematic review and meta-analysis

Objective To systematically evaluate the predictive value of abnormal uteroplacental and fetal Doppler indices for adverse perinatal outcomes in patients with hypertensive disorders of pregnancy (HDP), quantify the strength of association, and assess the certainty of evidence to optimize prenatal monitoring protocols....

Peng Zhou, Zhong-Feng Tang, Si-Yuan Li et al. · Frontiers in Medicine · 0 citations