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Wen-Guo Cui

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Sep 2026

Oxygen sensing governs tissue regeneration, degeneration, and ageing.

Hypoxia is not simply harmful or protective. Recent studies suggest that hypoxia-inducible factor 1-alpha (HIF-1α) acts as a time- and context-sensitive regulator of tissue-state transitions. We propose that transient HIF-1α activity enables regenerative entry, whereas persistent or unresolved signalling promotes malad...

Yi-Han Li, Ding Zhao, Wen-Guo Cui · 0 citations

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