A recombinant attenuated PRRSV vaccine expressing the PCV2 capsid protein confers protective immunity in pigs.
RHuN4-F112-Cap has potential as a bivalent live-vector vaccine candidate against PRRSV and PCV2, and vaccinated piglets showed reduced DNA loads and milder lymphoid lesions after PCV2 challenge, and reduced clinical signs, lower PRRSV RNA loads, milder pulmonary lesions, and improved survival after highly pathogenic PR...