Sep 2026
NQO1‑activated self‑reinforcing bimetallic nanoplatform triggers ferroptosis and cuproptosis for osteosarcoma therapy.
The CFCM/VK3 nanoplatform demonstrates significant tumor suppression and excellent biosafety in an osteosarcoma mouse model, establishing a new paradigm of metal-ion interference therapy that leverages the mutual dependency between iron and copper for self-amplifying antitumor effects.
Ye Zhang, Qing-Qing Bai, Yan-Hua Zhong et al.
· Colloids and Surfaces B: Bio... · 0 citations