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Open access Oct 2026

DIA Quantitative Proteomic Analysis Reveals Early Proteomic Responses to Honeybee-Derived Melittin in Murine Breast Cancer Cells

Breast cancer remains a major clinical challenge because of its molecular heterogeneity, therapeutic resistance, and disease recurrence. Melittin, the principal bioactive peptide of honeybee venom, exhibits antitumor activity in multiple experimental models; however, its early proteome-wide effects in breast cancer cel...

Jun-Ling Zhu, Wen-Hua Xu, He Zang et al. · 0 citations
Open access Aug 2026

nce-miR-12220 is a vital regulator for microsporidian to infect honeybee via positive modulation of ATP-A and γ-tubulin genes

Microsporidia rely extensively on host resources, yet how parasite-derived microRNAs coordinate infection remains poorly understood. Here, we investigated the function of nce-miR-12220, a miRNA identified in Nosema ceranae spores, during infection of Apis mellifera workers. Target prediction, dual-luciferase assays, an...

Rui Guo, He Zang, Wenhua Xu et al. · 0 citations

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