Wen-Hui Zhang

Immune checkpoint inhibitor-related endocrinopathies: from immune crosstalk to predictive biomarkers and precision management

Immune checkpoint inhibitors (ICIs) have significantly prolonged patient survival in cancer therapy; however, overactivated immune responses can lead to endocrine immune-related adverse events (irAEs), primarily manifesting as thyroid dysfunction, hypophysitis, adrenal insufficiency, and insulin-dependent diabetes mell...