Author

Wen Huo

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Open access Sep 2026

ITGA5 promotes homologous recombination mediated radioresistance in esophageal squamous cell carcinoma by upregulating RAD51AP1 expression.

This work defines the ITGA5/FAK/β-catenin/MYC/RAD51AP1 pathway as a key mechanistic driver of radioresistance and validates ITGA5 as a potential clinical target for ESCC therapy.

Xin-Yi Huang, Jia-Yi Liu, Jiao Ren et al. · Oncogene · 0 citations

Review Open access Jul 2026

The role of macrophages in radiation-induced lung injury: from pathological mechanisms to therapeutic targets

Radiation-induced lung injury (RILI) is a major dose-limiting toxicity of chest radiotherapy (RT), and its occurrence and development are closely related to the complex role of macrophages. RT significantly modulates the recruitment and functional status of macrophages. In the early stage, macrophages predominantly exh...

Xiaochi Ma, Jie Lu, Tao Zhong et al. · Frontiers in Immunology · 0 citations