Author

Wen-Jie Fang

3 papers indexed here

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Open access Sep 2026

Deep Learning Based on DeepLabv3+ for Automated Identification, Segmentation, and Quantification of Fungi in Clinical Fluorescence Microscopy Images

Fungal fluorescence microscopy using Calcofluor White is a rapid and sensitive diagnostic tool for fungal infections. However, manual microscopic examination is limited by high subjectivity, observer fatigue, poor reproducibility, and a heavy reliance on professional expertise—particularly in high-throughput clinical s...

B. Du, Wen-Jie Fang, Fen-Yu Shu et al. · Mycopathologia · 0 citations

Open access Sep 2026

Outbreaks of fluconazole-resistant Candida parapsilosis are driven by low-biofilm-producing isolates that emerge under host selection

It is shown that FLCR-Cp isolates responsible for prolonged, multi-country outbreaks consistently exhibit a striking low-biofilm-producing (LBP) phenotype, overturning the assumption that robust biofilm formation drives outbreak persistence and identifying biofilm attenuation as an adaptive tradeoff that promotes immun...

F. Daneshnia, Deepika Gunasekaran, S. Bergin et al. · PLoS Biology · 2 citations · ⚡1

Open access Sep 2026

Tight junction suppression by candidalysin promotes gut-to-blood dissemination of Candida albicans

The dose-dependent effects of candidalysin on epithelial junction-associated proteins support a context-dependent contribution to intestinal pathogenesis and may reveal therapeutic targets to preserve mucosal integrity and prevent systemic candidiasis.

Ya-Hui Feng, Wen-Jie Fang, Ning Zhang et al. · Frontiers in Microbiology · 0 citations