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Wen-Jie Zheng

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Review Open access Sep 2026

Computed Tomography Angiography Findings and Clinical Characteristics of Aneurysms in Patients with Behçet's Disease: A Retrospective Study.

OBJECTIVE To retrospectively evaluate computed tomography angiography (CTA) findings and associated clinical features of aneurysms in patients with Behçet's disease (BD), with the aim of informing optimal management strategies. METHODS We reviewed BD patients with aneurysms admitted to our institution between 1997 an...

Chi Xu, Jian Wang, Qiong-Yu Liang et al. · 0 citations
Sep 2026

Efficacy and safety of upadacitinib in anti-TNF-refractory intestinal Behçet's disease: a single-center retrospective study.

OBJECTIVES To evaluate the efficacy and safety of upadacitinib in patients with anti-TNF -refractory intestinal Behçet's disease (BD). METHODS We conducted a single-center retrospective study using data from a maintained BD registry at Peking Union Medical College Hospital between July 2024 and April 2026. Seventeen...

Jing-Wen Wu, Jian-Mei Wang, Xiao-Yin Bai et al. · 0 citations
Open access Sep 2026

Cytotoxic lymphocyte death drives monocyte activation and TNF/IFN-γ synergism in TBK1 deficiency

Combined TNF and JAK inhibition as an effective therapeutic strategy for TBK1 deficiency is supported and cytotoxic lymphocytes are the primary drivers of aberrant cell death through a T cell-myeloid axis dependent on TNF/IFN-γ synergism.

Xu Han, Jialin Dai, Ji-Hong Xiao et al. · 0 citations

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