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Wen-Jin Liu

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Aug 2026

Distinct Transcriptional States of TDP-43 Pathology in an Alzheimer's Disease Mouse Model.

A transcriptional framework linking early TDP-43 stress responses to pathological aggregation in AD is provided, and potential upstream therapeutic targets are revealed, including ERK1/2, PI3K, small GTPases, and mRNA splicing pathways.

Ji-Chuan Liu, Wen-Jin Liu, Liqiang Yu et al. · 0 citations