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Wen-Jing Hu

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Open access Sep 2026

Development and internal–external validation of an interpretable machine learning model integrating clinical and polygenic predictors for coronary artery disease: a multicenter retrospective cohort study

Accurate primary-prevention risk stratification for coronary artery disease (CAD) remains challenging. We developed and internally validated a framework integrating clinical variables with a polygenic risk score (PRS). This three-center retrospective cohort included 2,067 adults without baseline CAD. The pri...

F. Lei, Xiang-Wen Xi, Zi-He Dang et al. · 0 citations

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