Porcine epidemic diarrhea virus (PEDV) continues to pose a significant threat to the swine industry, leading to high mortality in neonatal piglets and substantial economic losses. The emergence of antigenic variants often compromises vaccine efficacy, highlighting the need for novel antiviral strategies. This study inv...
This review examines the roles of four key frontiers, including organoid models, gene editing, AI-driven molecular design, and synthetic biology, and discusses how these technological frontiers contribute to disease modeling, target discovery, molecular design, and translational innovation.
The isolated and characterized a novel GIIc PEDV strain CHjx2025 from diarrheic piglets in Ji'an City, Jiangxi Province, China, highlighting the need for continuous surveillance and GIIc-specific vaccine development to control PED outbreaks.
Jin-Peng Fan, Yanling Liu, Wen-Qian Fu et al.· BMC Veterinary Research· 1 citation· ⚡1
This study generated and characterized a panel of monoclonal antibodies targeting the PDCoV S1 protein and identified five S1B-specific neutralizing antibodies that cross-react with S1B proteins from multiple human- and avian-origin deltacoronavirusess.
Jia-Ru Zhou, Ran Jing, Meng-Di Zhang et al.· mBio· 0 citations
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