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Wen-Jun Yan

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Review Open access Oct 2026

Global research trends and emerging themes of ketamine in perioperative neurocognitive disorders: a bibliometric analysis

Within the contemporary perioperative neurocognitive disorder (PND) framework, postoperative neurocognitive outcomes include postoperative delirium, delayed neurocognitive recovery, and postoperative neurocognitive disorder. Interest in ketamine and its enantiomers has increased, but the clinical literature on peri...

Jun Kang, Zi-Wei Wang, Jia-Xuan Bi et al. · 0 citations
Review Open access Oct 2026

Dexmedetomidine as a potential neuroprotective agent against Alzheimer’s disease: molecular mechanisms and therapeutic perspectives

Alzheimer’s disease (AD) is a neurodegenerative disorder characterized by extracellular deposition of amyloid-β (Aβ), intracellular hyperphosphorylation of microtubule-associated protein tau and chronic neuroinflammation. At present, effective disease-modifying therapies for AD remain limited. Dexmedetomidine (Dex),...

Jun Kang, Yong-Bo Duan, Jia-Xuan Bi et al. · 0 citations

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