Isorhoifolin regulates S1PR3-CK2-GSK3β axis and promotes neurite regrowth and functional recovery after traumatic brain injury.
A neuron-centric role for S1PR3 in regulating structural repair is delineated that is mechanistically distinct from the known functions of S1PRs in immune cells and defines mechanistically distinct yet coordinated neuronal and astrocytic pathways that are responsible for isorhoifolin-enhanced structural and functional...