Open access
Aug 2026
Tumor microenvironment-remodeling cell membrane biomimetic nanoplatform for activated imaging and cascade-amplified treatment of breast cancer.
BIMLM is developed as a biomimetic nanoplatform integrating lactate oxidase (LOX)-driven lactate exhaustion with MnO2-coated IR-780 for TME remodeling and self-amplifying ROS generation that enhances PDT/CDT efficacy while triggering metabolic starvation and ferroptosis, which collectively enable tumor eradication.
Boye Zhang, Yuli Chen, Pengyan Qiao et al.
· Journal of Advanced Research · 0 citations