Open access
Sep 2026
Emodin Suppresses the RAGE/ROCK1 Pathway to Modulate the Oligodendrocyte Lineage and Ameliorate Demyelination in Vascular Dementia Rats
ABSTRACT Background Vascular dementia (VD), a prevalent cognitive disorder mainly resulting from chronic cerebral hypoperfusion‐triggered white matter injury (WMI), takes regulation of oligodendrocyte (OL) lineage and restoration of remyelination as key therapeutic targets, whereas the precise role and mechanism of the...
Xue-Qing Wang, Xiu-Mei Dong, Cun-Bao He et al.
· CNS Neuroscience & Therapeut... · 0 citations