Author

Wen-Ping Yang

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Open access Aug 2026

Redox cycling of viral RNA polymerase controls picornavirus replication

Picornaviruses, including foot-and-mouth disease virus (FMDV), enterovirus 71 (EV71) and encephalomyocarditis virus (EMCV), are important pathogens that cause fever, herpes, and myocarditis in humans and animals. The interplay between picornaviruses and their hosts remains enigmatic. Here we perform porcine genome-wide...

Wei-Wei Li, Zhao-Yu Zhu, Wei Zhang et al. · Nature Communications · 0 citations

Open access Sep 2026

A859L Plays a Critical Role in Facilitating Efficient African Swine Fever Virus Replication

African swine fever virus (ASFV) is a highly pathogenic agent that poses a severe threat to the global swine industry. The biological function of A859L, an ASFV-encoded RNA helicase, remains largely elusive. Here, we show that A859L is highly conserved across diverse ASFV isolates and belongs to the SF2 superfamily of...

Xiang-Tao Zhu, Hong-Yu Yan, Wan-Hui Zhou et al. · Viruses · 0 citations