Author

Wen-Qi Tan

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Open access Sep 2026

Integrated multi-omics analysis reveals shared IFN-γ-associated monocyte signatures in primary Sjögren’s syndrome and Alzheimer’s disease

This study demonstrates that pSS and AD share IFN-γ-related immune-inflammatory features and identifies OAS3 as a candidate IFN-γ-responsive molecule that exhibits sustained responsiveness to IFN-γ stimulation and provides new insights into the shared IFN-γ-associated immune features.

Xiao-Han Zhang, Shao-Fu Yan, Ming-Hui Xu et al. · Frontiers in Immunology · 0 citations

Open access Jul 2026

ORC6 marks a replication-active malignant epithelial state and is associated with immune-low features in oral squamous cell carcinoma

Introduction Oral squamous cell carcinoma (OSCC) shows marked biological heterogeneity, but markers that connect malignant epithelial states with the tumor immune context remain limited. Origin recognition complex subunit 6 (ORC6) participates in DNA replication licensing, but its disease-specific role in OSCC is not w...

Shaofu Yan, Wenqi Tan, Yanxin Zhang et al. · Frontiers in Oncology · 0 citations