Wen-Rui Huang

Exercise-related interventions for cardiopulmonary function in adolescent idiopathic scoliosis: a systematic review and network meta-analysis

To compare the effects of exercise-related interventions on cardiopulmonary function in adolescents with adolescent idiopathic scoliosis (AIS). We searched PubMed, Embase, other databases, and trial registries for randomized controlled trials that reported cardiopulmonary outcomes in adolescents with AIS. Standardized...

Comparative efficacy of digital health intervention delivery modalities on quality of life, anxiety, and depression in coronary heart disease: a systematic review and network meta-analysis

Nonadherence to traditional cardiac rehabilitation and persistent psychological distress among patients with coronary heart disease (CHD) severely undermine desired therapeutic outcomes. Digital health interventions (DHIs) emerge as promising strategies to effectively tackle this adherence and mental health issue r...

Comparative efficacy and safety of PCSK9 inhibitors for lipoprotein(a) reduction: a systematic review and network meta−analysis

Lipoprotein(a) [Lp(a)] is a genetically determined cardiovascular risk factor that is largely unaffected by statins. Although PCSK9 inhibitors can lower Lp(a), comparative evidence among agents is limited. We conducted a systematic review and frequentist random−effects network meta−analysis of randomized c...

Effect of exercise intervention on chronic primary pelvic pain syndrome: A network meta-analysis.

BACKGROUND This network meta-analysis evaluates the comparative effectiveness of different exercise interventions for managing chronic primary pelvic pain syndrome (CPPPS) in men. We assessed their impact on the National Institutes of Health Chronic Prostatitis Symptom Index (NIH-CPSI) total score, including its pain,...

Cementless versus cemented fixation in robotic-assisted total knee arthroplasty: a systematic review and meta-analysis

Treatment strategies for functional hypogonadism in obese men: a systematic review and network meta-analysis.

Available treatments showed distinct outcome-specific effects, but no single strategy was consistently superior across all outcomes, and these findings should inform individualized treatment decisions rather than a definitive treatment ranking.