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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

Author

Wen-Wen Xin

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Open access Sep 2026

Development and Humanization of a Camelid-Derived Neutralizing Nanobody Targeting Botulinum Neurotoxin Type A

Purpose Botulinum neurotoxin (BoNT), produced by Clostridium botulinum, is one of the most potent neurotoxins, causing botulism, a potentially fatal paralytic disease. Among different serotypes, BoNT/A is the most potent and the primary cause of botulism. The receptor-binding domain (Hc) of BoNT is crucial for targetin...

Yu-Jia Jiang, Wen-Wen Xin, Jian-Sheng Lu et al. · 0 citations
Open access Oct 2026

Base-mismatched crRNA in CRISPR Enabled Universal One-pot Rapid Nucleic Acid Detection

This cost-effective, adaptable strategy can streamline RPA-CRISPR diagnostics for infectious disease surveillance and convert established two-step assays for Burkholderia pseudomallei and Brucella into one-pot formats.

Jian-Hao Xu, Xin Wang, Bing Yuan et al. · 0 citations

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