Open access
Aug 2026
A Multi-Model Strategy for Optimizing Hepatitis B Virus preS1 Epitope Recognition by the Antibody HzKR127
A structure-guided computational workflow for affinity-enhancing candidate mutations at the interface between the humanized neutralizing antibody HzKR127 and the HBV preS1 peptide epitope is developed, providing a prioritized list of candidates for experimental validation and a practical framework for the rational opti...
Wen-Qing Chen, Yuan-Zhong Tu, Kai Wang et al.
· Current Issues in Molecular... · 0 citations