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Author

Wen-Xiu Yuan

2 papers indexed here

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Open access Aug 2026

PFKM acts as a metabolic switch initiating donut-shaped mitochondrial remodeling to promote osteogenesis

Osteogenic differentiation requires sophisticated mitochondrial adaptation to meet bioenergetic demands, yet regulatory checkpoints governing this organelle reorganization remain poorly defined. Through single-cell RNA sequencing reanalysis and metabolic intervention, this study unveils a non-canonical signaling role f...

Nengwen Huang, Yang Li, Jie Lu et al. · 0 citations
Open access Aug 2026

Strontium-incorporated thermoresponsive hydrogel platform co-delivering graphene oxide-mannose nanocomplexes: An osteoimmunomodulatory strategy for periodontitis therapy

The results demonstrate that the GM-Sr@Hydrogel functions as a potent osteoimmune regulator, evidenced by significant attenuation of periodontal inflammation and robust preservation of alveolar bone mass and establish the GM-Sr@Hydrogel as a promising translational platform for the management of periodontitis.

Linxin Chen, Jia-Yi Cai, Lin Liu et al. · 0 citations

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