Traditional Chinese herbal formula Huo Luo Xiao Ling Dan ameliorates rheumatoid arthritis by suppressing inflammation and oxidative stress via the AGE/RAGE/NF‑κB signaling pathway.
Rheumatoid arthritis (RA) is a chronic autoimmune pathology that arises chiefly from the dysregulated activation of fibroblast-like synoviocytes. The traditional Chinese herbal formula Huo Luo Xiao Ling Dan (HLXL) has unclear mechanisms in RA treatment. This work combined network pharmacology with both cellular and ani...